Rheumatoid factor lsotypes and cancer prognosis
نویسندگان
چکیده
منابع مشابه
Comparative Measurement of Rheumatoid Factor in Serum and Synovial Fluid of Rheumatoid Arthritis Patients by ELISA and Latex-Agglutination Test
Rheumatoid factors (RF) are autoantibodies with specificity for the Fc portion of human IgG. Production of RF is a characteristic feature of rheumatoid arthritis (RA) and is detectable in high titer in about 90% of these patients. In this study, we measured total IgM, IgA, IgMRF and IgARF in serum and synovial fluid of 45 RA patients by ELISA and the results were compared with those obtained b...
متن کاملDifferential Expression of Rheumatoid Factor-Associated Cross-Reactive Idiotypes in Iranian Seropositive and Seronegative Patients with Rheumatoid Arthritis
High levels of rheumatoid factors (RF) are detectable in serum of the majority of patients with rheumatoid arthritis (RA), but 5-10% of patients remain seronegative (SN). Despite clinical and genetic similarities between these two subsets of RA, it has been proposed that they may be regarded as distinct clinical entities. Methods: In the present study a panel of monoclonal antibodies (mAb) rec...
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PURPOSE Vascular endothelial growth factor (VEGF) promotes angiogenesis and vascular permeability. The VEGF gene is polymorphic. We investigated the prognostic significance of three VEGF single nucleotide polymorphisms (SNP) in esophageal cancer. EXPERIMENTAL DESIGN Three hundred sixty-one patients were genotyped for three VEGF SNPs (-460T/C, 405G/C, and 936C/T) using DNA extracted from prosp...
متن کاملCourse and prognosis in rheumatoid arthritis.
In a previous communication (Duthie, Thompson, Weir, and Fletcher, 1955), the results of treatment in hospital and the subsequent progress of a group of patients with rheumatoid arthritis were described. At the time of the first report the mean duration of follow-up was 24-4 months. Certain factors which might influence prognosis were considered. It was concluded that improvement following trea...
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ژورنال
عنوان ژورنال: Cancer
سال: 1992
ISSN: 0008-543X,1097-0142
DOI: 10.1002/1097-0142(19920415)69:8<2160::aid-cncr2820690824>3.0.co;2-z